Morphine Interaction with Aspirin: a Double-Blind, Crossover Trial in Healthy Volunteers
نویسندگان
چکیده
منابع مشابه
Safety of Aqueous Extract of Tinospora cordifolia (Tc) in Healthy Volunteers: A Double Blind
It is a common misconception that ayurvedic medicines (traditional Indian system of medicine) are always safe. In fact, they also pose serious health risks either in the form of adverse reactions or in the form of drug interactions. Over 80% of our population takes ayurvedic medicines. To evaluate the safety profile of Tinospora cordifolia in healthy volunteers using a battery of haematological...
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PURPOSE Primary vascular dysregulation (PVD) is a condition in which the response to cold temperature or external stimuli is abnormal. We investigated whether triflusal use results in amelioration of PVD symptoms and improvement of several related parameters compared with aspirin. MATERIALS AND METHODS Eighty-eight PVD patients (54% female, 56±8 years) were randomly selected to receive either...
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Objective: Some of the adverse effects of aspirin including peptic ulcers, gastrointestinal bleeding and aspirin resistance compelled researchers to find a suitable alternative with fewer adverse effects. In this clinical trial, we aimed to find the effective antiplatelet dose of garlic. Materials and Methods: This randomized controlled clinical trial (RCT) was conducted on 62 healthy volunteer...
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In this double-blind crossover trial, naproxen (750 mg/day) was compared to placebo for the treatment of osteoarthrosis of the hip and knee. Patients were randomly assigned to treatment with either naproxen or placebo for 4 weeks and then to treatment with the alternate agent for a second 4-week period. 8 out of 9 objective and subjective measurements of drug efficacy clearly differentiated nap...
متن کاملReflexology has an acute (immediate) haemodynamic effect in healthy volunteers: a double-blind randomised controlled trial.
UNLABELLED Reflexologists claim that massage to specific points of the feet increases blood supply to internal organs. This study measured changes in cardiovascular parameters in subjects receiving reflexology to areas of their feet thought to correspond to the heart (intervention) compared with other areas which are not (control). METHOD 16 reflexology-naive healthy volunteers received an ac...
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ژورنال
عنوان ژورنال: Journal of Pharmacology and Experimental Therapeutics
سال: 2018
ISSN: 0022-3565,1521-0103
DOI: 10.1124/jpet.117.247213